Colorectal cancer overview

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Article Introduction Colorectal cancer CRC is the third most common cancer in men and the second most common in women. Although screening, papillomas growth and increased awareness have augmented the number of cases in the non-metastatic setting, approximately one in four individuals with CRC will be diagnosed in stage IV. Additionally, because this improvement in survival has also been associated with substantial health care financial burden, appropriate selection of patients for specific treatments is of utmost importance. Currently, there are several biomarkers that help clinicians in making the optimal treatment decision: KRAS, NRAS, BRAF mutations, human epidermal growth factor receptor 2 HER2 amplification and microsatellite instability MSI or mismatch repair MMRthey all play a significant role in the process, facilitating selection of the right treatment for the right patient.

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This article has been cited by other articles in PMC. Methods A retrospective study of patients with small bowel cancers admitted to a tertiary emergency center, over the past 15 years. Results There were 57 patients with small bowel cancer, representing 0.

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What is Colorectal Cancer? papiloma cade ce să facă

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