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Laryngeal papillomatosis incidence Laryngeal papilloma incidence The virus is transmitted mainly sexually but epidemiological and clinical data suggest sufficient evidence also for other routes of transmission. Newborns can acquire the infection intrauterinely and perinatally or by horizontal ways of transmission. Laryngeal papillomatosis prevalence We aimed to describe, by reviewing the literature, the damaging effect of HPV on pregnancy outcomes and the risk of the newborn to develop recurrent respiratory papillomatosis. Also, we assessed papilloma histology risk of HPV laryngeal papillomatosis incidence and quadrivalent vaccine in pregnancy and paediatric population.